General Information

  • ID:  hor003174
  • Uniprot ID:  E9H0Y1
  • Protein name:  RYamide 2
  • Gene name:  NA
  • Organism:  Daphnia pulex (Water flea)
  • Family:  NPY family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  SEVRSRVASRSADERFFGGPRF
  • Length:  22
  • Propeptide:  MFPRRPYACAKLAYYIQQLKKPHVMARKESVFWLFCTLALMMSVVLVDAQTFFTNGRYGKRSEVRSRVASRSADERFFGGPRFGRSGNGGIVLGNSELDARNPERFFIGSRYGKRSEMEQIVPSPQVDESTSNSQEKETFLECNPIGIEQLYHCIERLKSAHHFDLMQHQQV
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9H0Y1-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor003174_AF2.pdbhor003174_ESM.pdb

Physical Information

Mass: 288847 Formula: C108H169N37O33
Absent amino acids: CHIKLMNQTWY Common amino acids: R
pI: 11.9 Basic residues: 5
Polar residues: 6 Hydrophobic residues: 7
Hydrophobicity: -82.73 Boman Index: -8802
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 35.45
Instability Index: 7407.73 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones